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Inclusion or exclusion of intratumoral vessels in relative cerebral blood volume characterization in low-grade gliomas: does it make a difference?

Research output: Contribution to journalArticle

  • G Brasil Caseiras
  • J S Thornton
  • T Yousry
  • C Benton
  • J Rees
  • Adam Waldman
  • H R Jäger

Related Edinburgh Organisations

Original languageEnglish
Pages (from-to)1140-1
Number of pages2
JournalAmerican Journal of Neuroradiology
Issue number6
Publication statusPublished - 29 Jun 2008


We assessed the influence of inclusion (method 1) and exclusion (method 2) of intratumoral vessels when determining maximum relative cerebral blood volume (rCBVmax) in 3 types of low-grade gliomas (LGGs): astrocytomas, oligoastrocytomas, and oligodendrogliomas. Method 1 yielded significantly higher mean rCBVmax than method 2. However, only method 2 demonstrated a significant (P = .026) association between rCBVmax and membership of a differently ranked histologic category. Exclusion of intratumoral vessels appears, therefore, preferable when determining rCBVmax in LGGs.

    Research areas

  • Blood Volume, Brain Neoplasms, Cerebrovascular Circulation, Glioma, Humans, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Neovascularization, Pathologic, Reproducibility of Results, Sensitivity and Specificity, Journal Article

ID: 46189868