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Individual anatomical networks, constructed from grey matter MRI scans

Research output: Contribution to conferencePoster

Original languageEnglish
Publication statusPublished - 2010
Event16th Annual Meeting of the Organization for Human Brain Mapping - Palau de Congressos de Catalunya, Barcelona, Spain
Duration: 6 Jun 201010 Jun 2010

Conference

Conference16th Annual Meeting of the Organization for Human Brain Mapping
CountrySpain
CityBarcelona
Period6/06/1010/06/10

Abstract

Recently graph theoretical techniques have demonstrated that functional and structural MRI scans show a small-world topology (Bullmore & Sporns, 2009). A small world topology is argued to be evolutionary optimal, as it minimizes wiring length while optimizing network connectivity (Chklovskii et al., 2004). While techniques exist to extract individual networks from functional MRI and DTI data, no such technique exists for grey matter. The cortex is very variable over people, a property related to individual differences in cognitive function (Kennedy et al., 1998).
We developed a method to construct individual anatomical networks from grey matter structural MRI scans. The method is sensitive for focal abnormalities that are of most interest in clinical populations, because it operates in the scan’s native space, thereby minimizing addition of noise from registration and warping procedures. The method was applied to healthy subjects to assess its validity and stability.

Event

16th Annual Meeting of the Organization for Human Brain Mapping

6/06/1010/06/10

Barcelona, Spain

Event: Conference

ID: 18474908