Edinburgh Research Explorer

Insulin immuno-neutralization in fed chickens: effects on liver and muscle transcriptome

Research output: Contribution to journalArticle

  • Jean Simon
  • Dragan Milenkovic
  • Estelle Godet
  • Cedric Cabau
  • Anne Collin
  • Sonia Métayer-Coustard
  • Nicole Rideau
  • Sophie Tesseraud
  • Michel Derouet
  • Sabine Crochet
  • Estelle Cailleau-Audouin
  • Christelle Hennequet-Antier
  • Christian Gespach
  • Tom E Porter
  • Michel J Duclos
  • Joëlle Dupont
  • Larry A Cogburn

Related Edinburgh Organisations

Original languageEnglish
Pages (from-to)283-92
Number of pages10
JournalPhysiological Genomics
Volume44
Issue number5
DOIs
Publication statusPublished - 1 Mar 2012

Abstract

Chickens mimic an insulin-resistance state by exhibiting several peculiarities with regard to plasma glucose level and its control by insulin. To gain insight into the role of insulin in the control of chicken transcriptome, liver and leg muscle transcriptomes were compared in fed controls and "diabetic" chickens, at 5 h after insulin immuno-neutralization, using 20.7K-chicken oligo-microarrays. At a level of false discovery rate

    Research areas

  • Animal Feed, Animals, Antibodies, Neutralizing, Chickens, Gene Expression Regulation, Insulin, Insulin Antibodies, Liver, Metabolic Networks and Pathways, Microarray Analysis, Muscle, Skeletal, Neutralization Tests, Proteins, Transcriptome

ID: 13077774