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Intracellular delivery of a catalytic organometallic complex

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http://xlink.rsc.org/?DOI=C7CC02988H
Original languageEnglish
JournalChemical Communications
Early online date6 Jun 2017
DOIs
Publication statusE-pub ahead of print - 6 Jun 2017

Abstract

A homogeneous carbene-based palladium catalyst was conjugated to a cell-penetrating peptide, allowing intracellular delivery of catalytically active Pd complexes that demonstrated bioorthogonal activation of a profluorophore within prostate cancer cells.

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