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Meta-analysis of pre-clinical studies of early decompression in acute spinal cord injury: a battle of time and pressure

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    Rights statement: Copyright: © 2013 Batchelor et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0072659
Original languageEnglish
Pages (from-to)e72659
JournalPLoS ONE
Volume8
Issue number8
DOIs
Publication statusPublished - 2013

Abstract

The use of early decompression in the management of acute spinal cord injury (SCI) remains contentious despite many pre-clinical studies demonstrating benefits and a small number of supportive clinical studies. Although the pre-clinical literature favours the concept of early decompression, translation is hindered by uncertainties regarding overall treatment efficacy and timing of decompression.

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