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Prediction of Depression in Individuals at High Familial Risk of Mood Disorders Using Functional Magnetic Resonance Imaging

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http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0057357
Original languageEnglish
Pages (from-to)e57357
JournalPLoS ONE
Volume8
Issue number3
DOIs
Publication statusPublished - 6 Mar 2013

Abstract

Bipolar disorder is a highly heritable condition. First-degree relatives of affected individuals have a more than a ten-fold increased risk of developing bipolar disorder (BD), and a three-fold risk of developing major depressive disorder (MDD) than the general population. It is unclear however whether differences in brain activation reported in BD and MDD are present before the onset of illness.

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