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Probe for evaluating the absorbing and transport scattering properties of turbid fluids using low-cost time-of-flight technology

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Original languageEnglish
Pages (from-to)55009
JournalJournal of Biomedical Optics
Volume22
Issue number5
Early online date25 May 2017
DOIs
Publication statusE-pub ahead of print - 25 May 2017

Abstract

A probe is described that when immersed into a highly scattering fluid provides a measurement of its scattering and absorbing properties at a single optical wavelength. It uses recently available low-cost proximity sensor modules to estimate the mean flight times of photons diffusely transmitted between near-infrared sources and detectors at two different separations. The probe has been designed with a specific application for enabling the rapid and efficient production of fluids, which mimic the optical properties of biological tissues. The potential of the device is demonstrated using precalibrated solutions of intralipid, an intravenous nutrient, and absorbing dye. It is shown that a combination of time-of-flight measurements at two source–detector separations can uniquely specify the absorption coefficient and the transport scattering coefficient.

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