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Quality and outcomes in global cancer surgery: protocol for a multicentre, international, prospective cohort study (GlobalSurg 3)

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
JournalBMJ Open
Early online date24 May 2019
Publication statusE-pub ahead of print - 24 May 2019


Empirical, observational data relating to the diagnosis, management and outcome of
three common worldwide cancers requiring surgery is lacking. However, it has been
demonstrated that patients in low- and middle-income countries undergoing surgery
for cancer are at increased risk of death and major complications post-operatively.
This study aims to determine quality and outcomes in breast, gastric and colorectal
cancer surgery across worldwide hospital settings.
Methods and analysis
This multicentre, international prospective cohort study will be undertaken by any
hospital providing emergency or elective surgical services for breast, gastric or
colorectal cancer. Centres will collect observational data on consecutive patients
undergoing primary emergency or elective surgery for breast, gastric or colorectal
cancer during a 6-month period. The primary outcome is the incidence of mortality
and major complication rate at 30-days after cancer surgery. Infrastructure and care
processes in the treatment of these cancers worldwide will also be characterised.
Ethics and dissemination
This project will not affect clinical practice and has been classified as clinical audit
following research ethics review. The protocol will be disseminated through the
international GlobalSurg network.
Trial registration number

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