Edinburgh Research Explorer

RKappa: Software for Analyzing Rule-Based Models

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish
Title of host publicationModeling Biomolecular Site Dynamics: Methods and Protocols
EditorsWilliam S. Hlavacek
Place of PublicationNew York, NY
PublisherSpringer New York LLC
Number of pages28
ISBN (Print)978-1-4939-9102-0
Publication statusPublished - 2019


RKappa is a framework for the development, simulation, and analysis of rule-based models within the mature statistically empowered R environment. It is designed for model editing, parameter identification, simulation, sensitivity analysis, and visualization. The framework is optimized for high-performance computing platforms and facilitates analysis of large-scale systems biology models where knowledge of exact mechanisms is limited and parameter values are uncertain.

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