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Segmenting white matter structure from diffusion MRI

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Original languageEnglish
Title of host publicationICML Workshop on Statistics, Machine Learning and Neuroscience
Publication statusPublished - 2012

Abstract

While diffusion MRI (dMRI) promises an insight into white matter integrity in vivo by measuring the degree of anisotropy in water molecule diffusion in the brain, the axonal pathways that connect different brain regions together can only partially be segmented using current methods. This is principally due to the lack of contrast in the spin-echo echo-planar MRI volumes collected in this modality. Here we present Tissue Dependent Diffusion model, a novel method for estimating the tissue composition of each voxel in the brain from dMRI data, thereby providing a foundation for computing the volume of different pathways in both health and disease.

ID: 18505828