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Study of Transposable Elements and Their Genomic Impact

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Original languageEnglish
Title of host publicationTransposons and Retrotransposons
PublisherSpringer
Pages1-19
Number of pages19
Volume1400
ISBN (Electronic)978-1-4939-3372-3
ISBN (Print)978-1-4939-3370-9
DOIs
Publication statusPublished - 20 Feb 2016

Publication series

NameMethods in Molecular Biology

Abstract

Transposable elements (TEs) have been considered traditionally as junk DNA, i.e., DNA sequences that despite representing a high proportion of genomes had no evident cellular functions. However, over the last decades, it has become undeniable that not only TE-derived DNA sequences have (and had) a fundamental role during genome evolution, but also TEs have important implications in the origin and evolution of many genomic disorders. This concise review provides a brief overview of the different types of TEs that can be found in genomes, as well as a list of techniques and methods used to study their impact and mobilization. Some of these techniques will be covered in detail in this Method Book.

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