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Subpopulation of proepicardial cells is derived from the somatic mesoderm in the chick embryo

Research output: Contribution to journalArticle

  • Jan Schlueter
  • Thomas Brand

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Original languageEnglish
Pages (from-to)1128-37
Number of pages10
JournalCirculation Research
Issue number10
Publication statusPublished - 25 Oct 2013


The proepicardium (PE) is a transient structure forming at the venous pole of the heart and gives rise to the epicardium, fibroblasts, and smooth muscle cells. The embryological origin of the PE is presently unclear. Asymmetrical formation of the PE on the right inflow tract is a conserved feature of many vertebrate embryos, and in the chicken is under the control of fibroblast growth factor 8 and snail homolog 1.

    Research areas

  • animals, basic helix-loop-helix transcription factors, chick embryo, fibroblast growth factor 8, mesoderm, pericardium, signal transduction, stem cells, transcription factors, twist transcription factor

ID: 13281940