Research output: Contribution to journal › Article › peer-review
Rights statement: Author's peer reviewed manuscript as accepted for publication.
Accepted author manuscript, 1.26 MB, Word document
Original language | English |
---|---|
Journal | Bioorganic & Medicinal Chemistry Letters |
Volume | 27 |
Issue number | 9 |
Early online date | 9 Mar 2017 |
DOIs | |
Publication status | Published - May 2017 |
A series of potent, competitive and highly selective kynurenine monooxygenase inhibitors have been discovered via a substrate-based approach for the treatment of acute pancreatitis. The lead compound demonstrated good cellular potency and clear pharmacodynamic activity in vivo.
ID: 34217095