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The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium

Research output: Contribution to journalArticle

  • Martin Ringwald
  • Vivek Iyer
  • Jeremy C Mason
  • Kevin R Stone
  • Hamsa D Tadepally
  • James A Kadin
  • Carol J Bult
  • Janan T Eppig
  • Darren J Oakley
  • Sebastien Briois
  • Elia Stupka
  • Vincenza Maselli
  • Damian Smedley
  • Songyan Liu
  • Jens Hansen
  • Richard Baldock
  • Geoff G Hicks
  • William C Skarnes

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    Rights statement: This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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http://nar.oxfordjournals.org/content/39/suppl_1/D849
Original languageEnglish
Pages (from-to)D849-D855
JournalNucleic Acids Research
Volume39
Issue numberDatabase issue
DOIs
Publication statusPublished - Jan 2011

Abstract

The International Knockout Mouse Consortium (IKMC) aims to mutate all protein-coding genes in the mouse using a combination of gene targeting and gene trapping in mouse embryonic stem (ES) cells and to make the generated resources readily available to the research community. The IKMC database and web portal (www.knockoutmouse.org) serves as the central public web site for IKMC data and facilitates the coordination and prioritization of work within the consortium. Researchers can access up-to-date information on IKMC knockout vectors, ES cells and mice for specific genes, and follow links to the respective repositories from which corresponding IKMC products can be ordered. Researchers can also use the web site to nominate genes for targeting, or to indicate that targeting of a gene should receive high priority. The IKMC database provides data to, and features extensive interconnections with, other community databases.

    Research areas

  • Adrenocortical Hyperfunction/etiology, Analysis of Variance, Animals, Animals, Newborn, Behavior, Animal/ physiology, Body Weight/physiology, Exploratory Behavior/physiology, Hydrocortisone/metabolism, Male, Saliva/chemistry, Stress, Psychological/complications/ metabolism/ physiopathology, Swine, Time Factors

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