Research output: Contribution to journal › Article › peer-review
Rights statement: Copyright © 2004, American Society for Microbiology
Final published version, 1.84 MB, PDF document
| Original language | English |
|---|---|
| Pages (from-to) | 5446-5451 |
| Number of pages | 6 |
| Journal | Infection and Immunity |
| Volume | 72 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Sep 2004 |
The role of the neuroendocrine environment in the pathogenesis of enteric bacterial infections is increasingly being recognized. Here we report that norepinephrine augments Escherichia coli O157:H7-induced intestinal inflammatory and secretory responses as well as bacterial adherence to intestinal mucosa in a bovine ligated ileal loop model of infection. Norepinephrine modulation of enteritis and adherence was dependent on the ability of E. coli O157:H7 to form attaching and effacing lesions.
ID: 4079655
