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The systems biology simulation core algorithm

Research output: Contribution to journalArticle

  • Roland Keller
  • Alexander Dörr
  • Akito Tabira
  • Akira Funahashi
  • Michael J Ziller
  • Richard Adams
  • Nicolas Rodriguez
  • Nicolas Le Novère
  • Noriko Hiroi
  • Hannes Planatscher
  • Andreas Zell
  • Andreas Dräger

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    Rights statement: © 2013 Keller et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Original languageEnglish
Article number55
JournalBMC Systems Biology
Publication statusPublished - 2013


With the increasing availability of high dimensional time course data for metabolites, genes, and fluxes, the mathematical description of dynamical systems has become an essential aspect of research in systems biology. Models are often encoded in formats such as SBML, whose structure is very complex and difficult to evaluate due to many special cases.

    Research areas

  • Algorithms, Models, Statistical, Systems Biology

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