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Topological and entropic repulsion in biopolymers

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Original languageEnglish
Article numberL09002
Pages (from-to)-
Number of pages11
Journal Journal of Statistical Mechanics: Theory and Experiment
DOIs
StatePublished - Sep 2009

Abstract

We estimate numerically the entropic repulsion felt by two or more approaching polymers with fixed topology. Our results complement field theory estimates valid for infinitely long chains. For two loops, the steric contributions to repulsion outweigh the topological one. When many loops come together, the entropy loss scales nonlinearly with their number. This could set a thermodynamic size for a 'rosette', a putative organizing motif of interphase chromosomes.

    Research areas

  • motif finding (theory), structures and conformations (theory), CELLULAR-ORGANIZATION, SPATIAL-ORGANIZATION, POLYGONS, TRANSCRIPTION, DIMENSIONS, CHROMOSOME, POLYMERS, LINKING

ID: 1451917