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Using transcriptome profiling to characterize QTL regions on chicken chromosome 5

Research output: Contribution to journalArticle

  • Guillaume Le Mignon
  • Colette Désert
  • Frédérique Pitel
  • Sophie Leroux
  • Olivier Demeure
  • Gregory Guernec
  • Behnam Abasht
  • Madeleine Douaire
  • Pascale Le Roy
  • Sandrine Lagarrigue

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    Rights statement: This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Original languageEnglish
Pages (from-to)575
JournalBMC Genomics
Volume10
DOIs
Publication statusPublished - 2009

Abstract

Although many QTL for various traits have been mapped in livestock, location confidence intervals remain wide that makes difficult the identification of causative mutations. The aim of this study was to test the contribution of microarray data to QTL detection in livestock species. Three different but complementary approaches are proposed to improve characterization of a chicken QTL region for abdominal fatness (AF) previously detected on chromosome 5 (GGA5).

    Research areas

  • Abdominal Fat, Animals, Chickens, Chromosomes, Female, Gene Expression Profiling, Humans, Liver, Male, Models, Genetic, Mutation, Oligonucleotide Array Sequence Analysis, Quantitative Trait Loci, Reproducibility of Results, Reverse Transcriptase Polymerase Chain Reaction

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